71. R. Wang, U. Illangovan, A.K. Robinson, V. Schirf, P.M. Schwarz, E.M. Lafer, B. Demeler, A.P. Hinck, and C.A. Kim. Structural Transitions of the RING1B C-terminal Region upon Binding the Polycomb cbox Domain. Biochemistry 47:8007-8015 (2008). Epub 2008 July 11. PMID: 18616292.

70. J.P. Schuermann, J. Jiang, J. Cuellar, O. Llorca, L. Wang, L.D. Gimenez, S. Jin, A.B. Taylor, B. Demeler, K. Morano, P.J. Hart, J.M. Valpuesta, E.M. Lafer, and R. Sousa. Structure of the Hsp110:Hsc70 Nucleotide Exchange Machine. Molecular Cell 31: 232-243 (2008). Epub 2008 Jun 12. PMID: 18550409

69. M.L Ferguson, K. Prasad, H. Boukari, D.L. Sackett, S. Krueger, E.M. Lafer, R. Nossal. Clathrin Triskelia Show Evidence of Molecular Flexibility. Biophysical Journal 95: 1945-1955 (2008). Epub 2008 May 23. PMID: 18502808

68. A. Martin, V. David, J.S. Laurence, P.S. Schwarz, E.M. Lafer, A.-M. Hedge, and P.S.N. Rowe. Degradation of MEPE, DMP1 and Release of SIBLING ASARM-peptides (minhibins): ASARM-peptides(s) are Directly Responsible for Defective Mineralization in HYP. Endocrinology 149: 1757-1772 (2008). PMID: 18162525

67. J. Jiang, E.G. Maes, A. Taylor, L. Wang, A.P. Hinck, E.M. Lafer, and R. Sousa. Structural Basis of J Cochaperone Binding and Regulation of Hsp70. Molecular Cell 28: 422-433 (2007). PMID: 17996706

66. E.M. Lafer. Synaptic Vesicle Recycling. Handbook of Neurochemistry and Molecular Neurobiology 11: Neural Membranes and Transport, Springer, edited by A. Lajtha, and M.E.A. Reithin (2007).

65. R. Sousa and E.M. Lafer. Keep the Traffic Moving: Mechanism of the Hsp70 Motor. Traffic 7: 1596-1603 (2006). PMID: 17026666

64. M. Ferguson, K. Prasad, D.L. Sackett, H. Boukari, E.M. Lafer and R. Nossal. The Conformation of a Clathrin Triskelion in Solution. Biochemistry 45: 5916-22 (2006). PMID: 16669634

63. A.J. Jin, K. Prasad, P.D. Smith, E.M. Lafer and R.J. Nossal. Measuring the Elasticity of Clathrin Coated Vesicles via Atomic Force Microscopy. Biophysical Journal 90:3333-44 (2006). PMID: 16511258

62. G.J. Augustine, J.R. Morgan, C. Villalba-Galea, S. Jin, K. Prasad, and E.M. Lafer. Clathrin and Synaptic Vesicle Endocytosis: Studies at the Squid Giant Synapse. Biochemical Society Transactions 34:68-72 (2006). PMID: 16417485

61. J. Jiang, E.M. Lafer, and R. Sousa. Crystallization of a Functionally Intact Bovine Hsc70. Acta Crystallograph Sect F Struct Biol Cryst Commun 62: 39-43 (2006). PMID: 16511258

60. J. Jiang, K. Prasad, E.M. Lafer and R. Sousa. Structural Basis of Interdomain Communication in the Hsc70 Chaperone. Molecular Cell 20:513-524 (2005). PMID: 16307916.

59. S.Yu, X. Yin, E.M. Lafer and J.X. Jiang. Developmental Regulation of the Direct Interaction between the Intracellular Loop of Connexin 45.6 and the C-terminus of Major Intrinsic Protein (Aquaporin-0). J. Biol. Chem. 280:22081-90 (2005). PMID: 15802270.

58. P.S.N. Rowe, I.R. Garrett, P.M. Schwarz, D.L. Carnes, E.M. Lafer, G.R. Mundy, and G.E. Gutierrez. Surface Plasmon Resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM-motif: A model for impaired mineralization in X-linked rickets (HYP). Bone 36:33-46 (2004).

57. A. Morón, I. Zakharova, J.V. Ferrer, G.A. Merrill, B. Hope, E.M. Lafer, Z.C. Lin, J.B. Wang, J.A. Javitch, A. Galli, and T.S. Shippenberg. Mitogen-Activated Protein Kinase Regulates Dopamine Transporter Surface Expression and Dopamine Transport Capacity. J. Neurosci. 23:8480-8 (2003).

56. J.R. Morgan, K. Prasad, S. Jin, G.J. Augustine, and E.M. Lafer. Eps15 Homology Domain – NPF Motif Interactions Regulates Clathrin Coat Assembly During Synaptic Vesicle Recycling. J. Biol. Chem. 278: 33583-92 (2003).

55. J. Jiang, A.B. Taylor, K. Prasad, Y. Ishikawa-Brush, P.J. Hart, E.M. Lafer, and R. Sousa. Structure-Function Analysis of the Auxilin J-Domain Reveals an Extended Hsc70 Interaction Interface. Biochemistry 42: 5748-5753 (2003).

54. J.R. Morgan, G.J. Augustine, E.M. Lafer. Synaptic Vesicle Endocytosis: The Races, Places, and Molecular Faces. NeuroMolecular Medicine 2: 101-114 (2002).

53. E.M. Lafer. Clathrin-Protein Interactions. Traffic 3: 513-520 (2002).

52. L. Carvelli, J.A. Morón, K.M. Kahlig, J.V. Ferrer, N. Sen, J.D. Lechleiter, L.M.F. Leeb-Lundberg, G. Merrill, E.M. Lafer, L.M. Ballou, T.S. Shippenberg, J.A. Javitch, R.Z. Lin, and A. Galli. PI 3-Kinase Regulation of Dopamine Uptake. J. Neurochem. 81: 859-869 (2002).

51. J.R. Morgan, K. Prasad, S. Jin, and G.J. Augustine, and E.M. Lafer. Uncoating of Clathrin-Coated Vesicles in Presynaptic Terminals: Roles for Hsc70 and Auxilin. Neuron 32: 289-300 (2001).

50. J.R. Morgan, E.M. Lafer, and G.J. Augustine. Rapid-Fire Synaptic Vesicle Exocytosis. Neuron 30: 5-7 (2001).

49. J.R. Morgan, K. Prasad, W. Hao, G.J. Augustine, and E.M. Lafer. A Conserved Clathrin Assembly Motif is Essential for Synaptic Vesicle Endocytosis. J. Neurosci. 20: 8667-8676 (2000).

48. J.R. Morgan, X. Xiao, M. Womack, K. Prasad, G.J. Augustine, E.M. Lafer. A Role for the Clathrin Assembly Domain of AP180 in Synaptic Vesicle Endocytosis. J. Neurosci. 19: 10201-10212 (1999).

47. W. Hao, Z. Luo, L. Zheng, K. Prasad, and E.M. Lafer. AP180 and AP-2 Interact Directly in a Complex that Cooperatively Assembles Clatrhin. J. Biol. Chem. 274: 22785-22794 (1999).

46. A.A. Profit, J. Chen, Q.-M. Gu, A. Chaudhary, K. Prasad, E.M. Lafer and G.D. Prestwich. Probing the Phosphoinositide Binding Site of the Clathrin Assembly Protein AP-2 with Photoaffinity Labels. Archives Biochem. Biophys. 357: 85-94 (1998).

45. W. Hao, Z. Tan, K. Prasad, K.K. Reddy, J. Chen, G.D. Prestwich, J.R. Falck, S.B. Shears, and E.M. Lafer. Regulation of AP-3 Function by Inositides: Identification of Phosphatidylinositol 3,4,5-trisphosphate as a Potent Ligand. J. Biol. Chem. 272: 6393-6398 (1997).

44. W. Ye and E.M. Lafer. Clathrin Binding and Assembly Activities of Expressed Domains of the Synapse-Specific Clathrin Assembly Protein AP-3. J. Biol. Chem. 270: 10933-10939 (1995)

43. W. Ye and E.M. Lafer. Bacterially Expressed F1-20/AP-3 Assembles Clathrin Into Cages With a Narrow Size Distribution: Implications for the Regulation of Quantal Size During Neurotransmission. J. Neurosci. Res. 41: 15-26 (1995).

42. W. Ye, N. Ali, M. Bembenek, S.B. Shears and E.M. Lafer. Inhibition of Clathrin Assembly by High-Affinity Binding of Specific Inositol Polyphosphates to the Synapse-Specific Clathrin Assembly Protein AP-3. J. Biol. Chem. 270: 1564-1568 (1995).

41. G. Bonner, E.M. Lafer and R. Sousa. The Thumb Subdomain of T7 RNA Polymerase Functions to Stabilize the Ternary Complex During Processive Transcription, J. Biol. Chem. 269, 25129-25136(1994).

40. G. Bonner, E.M. Lafer and R.Sousa. Characterization of a Set of T7 RNAP Active Site Mutants, J. Biol. Chem. 269, 25120-25128(1994).

39. S. Zhou, N. Hrinya Tannery, J. Yang, S. Puszkin, and E.M. Lafer. The Synapse-Specific Phospho-protein F1-20 is Identical to the Clathrin Assembly Protein AP-3. J. Biol. Chem., 268, 12655-12662 (1993).

38. G. Bonner, D. Patra, E.M. Lafer, and R. Sousa. Mutations in T7 RNA Polymerase that Support the Proposal for a Common Polymerase Active Site Structure. EMBO J. 11, 3767-3775 (1992).

37. S. Zhou, R. Sousa, N. Hrinya Tannery, and E.M. Lafer. Characterization of a Novel Synapse- Specific Protein: II. cDNA Cloning and Sequence Analysis of the F1-20 Protein, J. Neurosci. 12, 2144-2155 (1992).

36. R. Sousa, N. Hrinya Tannery, S. Zhou, and E.M. Lafer. Characterization of a Novel Synapse-Specific Protein: I. Developmental Expression and Cellular Localization of the F1-20 Protein and mRNA, J. Neurosci. 12, 2130-2143 (1992).

35. R. Sousa, D. Patra, and E.M. Lafer. Model for the Mechanism of Bactreiophage T7 RNAP Transcription Initiation and Termination. J. Mol. Biol. 224, 319-334 (1992).

34. D. Patra, E.M. Lafer, and R. Sousa. Isolation and Characterization of Mutant Bacteriophage T7 RNA Polymerases, J. Mol. Biol. 224, 307-318 (1992).

33. R. Sousa, Y.J. Chung, B.C. Wang, and E.M. Lafer. Preparation of Crystals of a Chimeric T7/T3 RNA Polymerase with T3 Promoter Specificity. J. Crystal Growth 122, 366-374 (1992).

32. R. Sousa, E.M. Lafer, and B.C. Wang. Preparation of Crystals of T7 RNA Polymerase Suitable For High Resolution X-Ray Structure Analysis. J. Crystal Growth 110, 237-246 (1991)

31. R. Sousa, Y.J. Chung, W.T. McCallister, B.C. Wang, and E.M. Lafer. Single Crystals of a Chimeric T7/T3 RNA Polymerase with T3 Promoter Specificity and a Non-Processive T7 RNAP Mutant. J. Biol. Chem. 265, 21430-21432 (1990).

30. Y.J. Chung, R.J. Sousa, J.P. Rose, E.M. Lafer, and B.C. Wang. Three-dimensional Structure of Bacteriophage T7 RNA Polymerase. In Advances in Applied Biotechnology Series, Vol. 7: Gene Regulation and AIDS: Transcriptional Activation, Retroviruses, and Pathogenesis, T.S. Papas, ed., Gulf Publishing Co., Houston, pp. 3-7 (1990).

29. Y.J. Chung, R.J. Sousa, J.P. Rose, E.M. Lafer, and B.C. Wang. Crystallographic Structure of Phage T7 RNA Polymerase at a Resolution of 4 Å. In Structure and Function of Nucleic Acids and Proteins, F. Wu and C.W. Wu, eds, pp. 55-59, Raven Press, N.Y (1990).

27. R. Sousa, N. Hrinya Tannery, and E.M. Lafer. Two New Monoclonal Antibodies Provide Immunohistochemical Evidence for the Unique Biochemical Similarity of the Mouse Globus Pallidus, Entopeduncular Nucleus, and Substantia Nigra pars Reticulata. Neuroscience 34, 403-410 (1990).

26. R. Sousa, J.P. Rose, Y.J. Chung, E.M. Lafer and B.C. Wang. Single Crystals of T7 RNA Polymerase. PROTEINS: Structure, Function, and Genetics 5, 266-270 (1989).

25. R. Sousa, N. Hrinya Tannery, and E.M. Lafer. In situ Hybridization Mapping of Glucocorticoid Receptor mRNA in Rat Brain. Molecular Endocrinology 3, 481-494 (1989).

24. E.M. Lafer, R. Sousa, and A. Rich. E. coli Z-DNA Binding Proteins: Purification, Monoclonal Antibody Generation, and Gene Isolation. J. Mol. Biol., 203, 511-516 (1988).

23. E.M. Lafer, R. Sousa, R. Ali, A. Rich and B.D. Stollar. The Effect of Anti-Z-DNA Antibodies on the B-DNA - Z-DNA Equilibrium. J. Biol. Chem. 261, 6438-6443 (1986).

22. E.M. Lafer, R. Sousa and A. Rich. Anti-Z-DNA Antibody Binding Can Stabilize Z-DNA in Relaxed and Linear Plasmids Under Physiological Conditions. EMBO Journal 13B, 3655-3660 (1985).

21. E.M. Lafer, R. Sousa, B. Rosen, A. Hsu and A. Rich. Isolation and Characterization of Z-DNA Binding Proteins From Wheat Germ. Biochemistry 24, 5070-5076 (1985).

20. B.D. Stollar, E.M. Lafer, A. Nordheim, M.L. Pardue and A. Rich. Immunological Probes for the Biological Significance of Z-DNA. In Progress in Clinical and Biological Research 172b, The Molecular Basis of Cancer, R. Rein, ed., Alan R. Liss, Inc., 323-332 (1985).

19. E.M. Lafer and B.D. Stollar. The Specificity of Antibodies Elicited by Poly(dG).Poly(dC). J. Biomolecular Structure and Dynamics 2, 487-494 (1984).

18. M. Tomasz, J.K. Barton, C.C. Magliozzo, D. Tucker, E.M. Lafer and B.D. Stollar. Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism. Proc. Natl. Acad. Sci. USA 80, 2874-2878 (1983).

17. A. Nordheim, L.J. Peck, E.M. Lafer, B.D. Stollar, J.C. Wang and A. Rich. Antibody Reactivity with Left-handed Z-DNA in Supercoiled Plasmids. Cold Spring Harbor Symp. Quant. Biol. 47, 93-100 (1983).

16. M.L. Pardue, A. Nordheim, E.M. Lafer, B.D. Stollar and A. Rich. Z-DNA and the Polytene Chromosome, Cold Spring Harbor Symp. Quant. Biol. 47, 171-176 (1983).

15. E. Lafer, A. Moller, R.P.C. Valle, A. Nordheim, A. Rich and B.D. Stollar. Antibody Recognition of Z-DNA. Cold Spring Harbor Symp. Quant. Biol. 47, 155-162 (1983).

14. H.J. Lipps, A. Nordheim, E.M. Lafer, D. Ammermann, B.D. Stollar and A. Rich. Antibodies Against Z-DNA React With the Macronucleus but not the Micronucleus of the Hypotrichous Ciliate Stylonichia Mytilus. Cell 32, 435-441 (1983).

13. E.M. Lafer, R.P.C. Valle, A. Moller, A. Nordheim, P.S. Schur, A. Rich and B.D. Stollar. Z-DNA Specific Antibodies in Human Systemic Lupus Erythematosus. J. Clin. Invest. 71, 314-321 (1983).

12. A. Nordheim, E.M. Lafer, L.J. Peck, J.C. Wang, B.D. Stollar and A. Rich. Negatively Supercoiled Plasmids Contain Left-handed Z-DNA Segments As Detected by Specific Antibody Binding. Cell 31, 309-318 (1982).

11. A. Nordheim, E.M. Lafer, A. Moller, B.D. Stollar, M.L. Pardue and A. Rich. Left-handed Z-DNA: A DNA Structure with Biological Function? In Embryonic Development, Part A: Genetic Aspects, Alan R. Liss, Inc., New York, NY, 101-113 (1982).

10. A. Moller, J.E. Gabriels, E.M. Lafer, A. Nordheim, A. Rich and B.D. Stollar. Monoclonal Antibodies Recognize Different Parts of Z-DNA. J. Biol. Chem. 257, 12081-12085 (1982).

9. J. Rauch, E. Lafer, C. Andrzejewski, B.D. Stollar and R.S. Schwartz. Monoclonal Lupus Autoantibodies. In Immunopathology, VIII International Symposium 1980, Academic Press, 285-292 (1982).

8. C.A. Andrzejewski, Jr., E.M. Lafer, J. Rauch, R.S. Schwartz and B. D. Stollar. The Use of Hybridomas in the Dissection of Autoimmune Phenomena. In Hybridomas in Cancer Diagnosis and Treatments, M.S. Mitchell and H.F. Oettgen, eds., Raven Press (1981).

7. A. Nordheim, M.L. Pardue, E.M. Lafer, A. Moller, B.D. Stollar and A. Rich. Antibodies to Left-Handed Z-DNA Bind to Interband Regions of Drosophila Polytene Chromosomes. Nature 294, 417-422 (1981).

6. E.M. Lafer, A. Moller, A. Nordheim, B. D. Stollar and A. Rich. Antibodies Specific for Left-Handed Z-DNA. Proc. Nat. Acad. Sci. 78, 3546-3550 (1981).

5. E.M. Lafer, J. Rauch, C.A. Andrzejewski, Jr., D. Mudd, B.C. Furie, B. Furie, R.S. Schwartz and B.D. Stollar. Polyspecific Monoclonal Lupus Autoantibodies Reactive with Both Polynucleotides and Phospholipids. J. Exp. Med. 153, 897-907 (1981).

4. R. Kisliuk, Y. Gaumont, E. Lafer, C. Baugh and J. Montgomery. Polyglutamyl Derivatives of Tetrahydrofolate as Substrates for Lactobacillus casei Thymidylate Synthase. Biochemistry 20, 929-934 (1981).

3. C.A. Andrzejewski, Jr., J. Rauch, E. Lafer, B.D. Stollar and R. Schwartz. Antigen Binding Diversity and Idiotypic Cross-Reactions Among Hybridoma Autoantibodies to DNA. J. of Immunol. 126, 226-231 (1981).

2. C.A. Andrzejewski, Jr., J. Rauch, E. Lafer, B.D. Stollar and R. Schwartz. Application of Hybridoma Technology for Analysis of Lupus Autoantibodies. Immunoregulation and Autoimmunity, Krakauer and Cathcart, eds., Elsevier North Holland, Inc., 55-59 (1981).

1. M. Papalian, E. Lafer, R. Wong and B.D. Stollar. Reaction of Systemic Lupus Erythematosus Antinative DNA Antibodies with Native DNA Fragments from 20-1200 Base Pairs. J. Clin. Invest. 65, 469-477 (1980).