My main interest is to study the roles of connexins in controlling development. Connexins molecules are well known to play significant roles in cell-cell communication, however, their roles in other cell signaling pathways, independent of gap-junction functions, such as anti-tumor, cardiac development, have not being studies extensively. My current project is to study how Cx45.6 or Cx50 (forming lens gap-junction) are involved in cell cycle regulation, which results in the control of lens development. Another project I am working now is studying the topology of SNAT4, an amino acid transporter. Amino acid transport across the plasma membrane provides critical substrates for protein bio-synthesis, hormone metabolism, regulation of cell growth, and production of metabolic energy. Topological studies help us in finding the structure - function relationship which can show a path in curing diseases.

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