Jean X. Jiang, Ph.D.
Lab Members

Banks E.A., Yu, X.S, Shi, Q. and Jiang, J.X. (2007). Promotion of lens epithelial-fiber differentiation by C-terminus of connexin 45.6, a role independent of gap junction communication. J Cell Sci. 120, 3602-3612.  Abstract on Medline  Full Text in HTML  Full Text in PDF(* Highlighted in “In This Issue”)

Jiang, J.X., Siller-Jackson, A.J., and Burra, S. (2007).  Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress. Front. Biosci. 12, 1450-1462. Abstract on Medline  Full Text in HTML  Full Text in PDF

Moret C., Dave, M.H., Schulz, N., Jiang, J.X., Verrey, F., Wagner, C.A.  (2007). Regulation of renal amino acid transporters during metabolic acidosis.  Am J Physiol Renal Physiol. 292, F555-566. Abstract on Medline  Full Text in HTML  Full Text in PDF

Gluhak-Heinrich, J., Gu, S., Pavlin, D., and Jiang, J.X. (2006).  Differential Mechanical Loading Stimulates Expression of Connexin 43 in Alveolar Bone Cells in the Tooth Movement Model. Cell Communica. Adhsion. 13, 115-125. Abstract on Medline  Full Text in HTML  Full Text in PDF

Cherian, P.P., Siller-Jackson, A.J., Gu, S., Wang, X., Bonewald, L.F., Sprague, E., and Jiang, J.X. (2005). Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin. Mol. Biol. Cell 16(7):3100-3106   (* Highlighted, Science STKE 291, tw242, 2005)   Abstract on Medline  Full Text in HTML  Full Text in PDF

Yu, X.S., Yin, X., Lafer, E.M., and Jiang, J.X. (2005). Developmental regulation of the direct interaction between the intracellular loop of connexin 45.6 and the C-terminus of major intrinsic protein (aquaporin-0). J. Biol. Chem. 280(23):22081-22090.   Abstract on Medline  Full Text in HTML  Full Text in PDF

Gu, S., Villegas, C.J., and Jiang, J.X. (2005). Differential regulation of amino acid transporter SNAT3 by insulin in hepatocytes. J. Biol. Chem. 280(28):26055-26062.   Abstract on Medline  Full Text in HTML  Full Text in PDF

Jiang, J.X., and Gu, S. (2005). Gap junction- and hemichannel-independent actions of connexins. Biochim. Biophys. Acta. 1711(2):208-214.   Abstract on Medline

Yu, X.S., and Jiang, J.X. (2004). Interaction of major intrinsic protein (aquaporin-0) with fiber connexins in lens development. J. Cell Sci. 117(6):871-880.   Abstract on Medline  Full Text in HTML  Full Text in PDF

Jiang, J.X., and Cherian, P.P. (2003). Hemichannels formed by Cx43 play an important role in the release of prostaglandin E2 by osteocytes in response to mechanical strain. Cell Communica. Adhesion 10(4-6):259-264.   Abstract on Medline

Cherian, P.P., Cheng, B., Gu, S., Sprague, E., Bonewald, L.F., and Jiang, J.X. (2003). Effects of mechanical strain on the function of gap junctions in osteocytes is mediated through the prostaglandin EP2 receptor. J. Biol. Chem. 278(44):43146-43156.   Abstract on Medline  Full Text in HTML  Full Text in PDF

Gu, S., Yu, X.S., Yin, X., and Jiang, J.X. (2003). Stimulation of lens cell differentiation by a gap junction protein Cx45.6. Invest. Opthalmol. & Visual Sci. 44(5):2103-2111.   Abstract on Medline  Full Text in HTML  Full Text in PDF

Jiang, J.X., Yin, X., Gu, S., Yu, X.S., Siller-Jackson, A.J., Priyadarshini, P., and Villegas, C.J. (2003). Function and regulation of gap junctions and connexins in the vertebrate eye lens. Recent Res. Devel. Biol. Chem. 1:307-318. ed. S.G. Pandalai, Research Signpost Press Inc.

Gu, S., Langlais, P., Liu, F., and Jiang, J.X. (2003). mNAT-3, an N-system amino acid transporter expressed in hepatocytes and regulated by an insulin-activated and PI3 kinase-dependent signaling. Biochem. J. 371(3):721-731.   Abstract on Medline  Full Text in PDF

Choi, D., Oh, H.J., Chang, U.J., Koo, S.K., Jiang, J. X., Hwang, S.Y., Lee, J.D., Yeoh, G.C., Shin, H.S., Lee, J-S., and Oh, B. (2002). In vivo differentiation of mouse embryonic stem cells into hepatocytes. Cell Transplant 11(4):359-368.   Abstract on Medline 

Yin, X., Gu, S., and Jiang, J.X. (2001). Regulation of lens connexin 45.6 by apoptotic protease, caspase-3. Cell Communica. Adhesion 8(4-6):373-376.   Abstract on Medline

Jiang, J.X., and Cheng, B. (2001). Mechanical stimulation of gap junctions in bone osteocytes is mediated by prostaglandin E2. Cell Communica. Adhesion 8(4-6):283-288.   Abstract on Medline

Yin, X., Gu, S., and Jiang, J.X. (2001). The development-associated cleavage of lens connexin 45.6 by caspase-3-like protease is regulated by casein kinase II-mediated phosphorylation. J. Biol. Chem. 276(37):34567-34572.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

Cheng, B., Kato, Y., Zhao, S., Luo, S., Luo, J., Sprague, E., Bonewald, L.F., and Jiang, J.X. (2001). Prostaglandin E2 is essential for gap junction-mediated intercellular communication between osteocytes in response to mechanical strain. Endocrinology 142(8):3464-3473.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

Gu, S., Adan-Rice, D., Leach, R.J., and Jiang, J.X. (2001). A novel human amino acid transporter, hNAT3: cDNA cloning, chromosomal mapping, genomic structure, expression and functional characterization. Genomics 74(3):262-272.   Abstract on Medline  Full Text in PDF 

Gu, S., Roderick, H.L., Camacho, P., and Jiang, J.X. (2001). Identification and characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport. J. Biol. Chem. 276(26):24137-24144.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

Cheng, B., Kato, Y., Luo, J., Zhao, S., Sprague, E., Bonewald, L.F., and Jiang, J.X. (2001). Expression of functional gap junctions and regulation by fluid flow in osteocyte-like MLO-Y4 cells. J. Bone Miner. Res. 16(2):249-259.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

Jiang, J.X. (2000). Use of retrovirus to express connexins. Methods in Molecular Biology, Gap Junction Protocols. ed. R. Bruzzone and C. Giaume, Humana Press Inc. pp 159-174.

Gu, S., Roderick, H.L., Camacho, P., and Jiang, J.X. (2000). Identification and characterization of a novel amino acid transporter expressed differentially in liver. Proc. Natl. Acad. Sci. USA 97(7):3230-3235.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

Yin, X., Jedrzejewski, P., and Jiang, J.X. (2000). Casein kinase II phosphorylates lens connexin 45.6 and is involved in its degradation. J. Biol. Chem. 275(10):6850-6856.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

He, D., Jiang, J.X., Taffet, S. M., and Burt, J.M. (1999). Formation of heteromeric gap junction channels by connexins 40 and 43 in vascular smooth muscle cells. Proc. Natl. Acad. Sci. USA. 96(11):6495-6500.   Abstract on Medline  Full Text in HTML  Full Text in PDF 

Jiang, J.X., and Goodenough, D.A. (1998). Phosphorylation of lens fiber connexins in lens organ cultures. Eur. J. Biochem. 255(1):37-44.   Abstract on Medline  Full Text in PDF 

Jiang, J.X., and Goodenough, D.A. (1998). Retroviral expression of connexins in embryonic chick lens. Invest. Ophthalmol. & Visual Sci. 39(3):537-543.   Abstract on Medline

Jiang, J.X., and Goodenough, D.A. (1998). Expression of retroviruses containing connexins in chick embryonic lens in situ. Gap Junctions. ed. R. Werner, IOS Press. 96-101.

Jiang, J.X., and Goodenough, D.A. (1996). Heteromeric connexon formation in lens gap junctions. Proc. Natl. Acad. Sci. USA 93(3):1287-1291.   Abstract on Medline  Full Text in PDF 

Jiang, J.X., White, T.W., and Goodenough, D.A. (1995). Changes in connexin expression and distribution during chick lens development. Dev. Biol. 168(2):649-661.   Abstract on Medline  Full Text in PDF

Jiang, J.X., White, T.W., Paul, D.L., and Goodenough, D.A. (1994). Molecular and functional characterization of lens fiber connexins. Progress in cell research. ed. Y. Kanno et al, Elsevier Science Press. 4, 377-381.

Jiang, J.X., White, T.W., Goodenough, D.A., and Paul, D.L. (1994). Molecular cloning and functional characterization of chick lens fiber connexin 45.6. Mol. Biol. Cell 5(3):363-373.   Abstract on Medline

Jiang, J.X., Paul, D.L., and Goodenough, D.A. (1993). Posttranslational phosphorylation of lens fiber connexin 46: a slow occurrence. Invest. Ophthalmol. & Visual Sci. 34(13):3558-3565.   Abstract on Medline

Any comments or suggestions about this site, please feel free to contact Webmaster.
Thank you for your visit.