Department of Biochemistry
 |
| Gregg B. Fields |
Gregg B. Fields, Robert A. Welch Foundation Distinguished Professor of Chemistry
| Education: | 1979: A.A., Chemistry, Broward Community College, Davie, FL 1982: B.S., Department of Chemistry, University of Florida, Gainesville, FL 1988: Ph.D., Department of Chemistry, Florida State University, Tallahassee, FL |
|---|---|
| Post Doctoral: | 1988-1991: Postdoctoral Scholar (with Professor Ken A. Dill), Department of Pharmaceutical Chemistry, University of California, San Francisco, CA |
| Other Faculty Positions: | 1991-1997: Assistant/Associate Professor, Department of Laboratory Medicine & Pathology, University of Minnesota, Minneapolis, MN 1997-2008: Professor, Department of Chemistry & Biochemistry, Florida Atlantic University, Boca Raton, FL |
| Web Page: | |
| Email: | FieldsG@uthscsa.edu |
| Phone: | 567-1312 |
| Room: | 542C.1 |
Dr. Fields' research interests are in the use of chemical approaches to better understand how protein three-dimensional structures influence cellular and enzymatic behaviors. Early studies by Dr. Fields included the systematic examination of mild methodologies for solid-phase synthesis of small proteins. Chemical approaches were used to develop “mini-protein” models for the study of cellular recognition processes, which in turn allowed for the mapping of protein domains involved in tumor cell binding and signal transduction. Mini-protein models have subsequently been utilized to dissect the mechanisms of collagen catabolism, and in the process have provided new avenues for protease inhibitor design. Dr. Fields has authored or coauthored more than 200 scientific publications and presented over 100 invited lectures. Dr. Fields is currently President of the American Peptide Society (2009-2011).
(1) Mechanism & Inhibition of Collagenolytic Activity; (2) Peptide-Amphiphile Biomimetics for Targeted Therapies; (3) Nanomedicine for Inhibition of Proteolysis and Targeted Drug Delivery